Research problem; systematic review; meta-analysis; mixed method; development of framework, research question/hypothesis; quantitative research designs to solve complex problems; validity and ethics of research; research methodologies; power analysis; data collection, and evaluation of properties of instruments; testing of assumptions, data analysis, interpretation and report the results regarding to advanced statistics focusing on  analysis of variance and covariance, multiple regression, logistic regression, factor analysis and discriminant analysis; critique of quantitative health and nursing research in the area of interest; dissemination and utilization of nursing research